<p>Trent Williams is questionable, potentially forcing Spencer Burford into a left tackle role. The line's cohesion and pass protection will be tested against the Saints' edge pressure.</p><p>Williams' status could influence blocking schemes and Jones's comfort, making Burford's performance pivotal for SF’s Week 2 success.</p>

Williams’ knee vet day adds to SF’s vulnerability on the line as Purdy’s status looms. Williams’ durability and presence are pivotal for SF’s run game and pass protection, and any absence could ripple through the offense’s efficiency.

Trent Williams anchors SF’s left side as a veteran cornerstone. His continued presence underpins McKivitz’s development and the overall stability of the 49ers’ line, a major factor in Purdy’s protection and SF’s run-game efficacy.

Williams’ absence threatens pass protection on Purdy’s blind side, complicating SF’s protection schemes. Backup tackles must step up quickly, and Williams’ long-term health will influence the offense’s stability and Purdy’s confidence.

Williams anchors the offensive line as a captain, providing continuity for Purdy’s pocket and McCaffrey’s run game. His veteran presence supports SF’s overall offensive rhythm and offers a reliable fantasy floor for the rushing and passing game behind SF’s protection schemes.